Workflow and Implications of membrane lipids

Introduction Membrane lipids play diverse roles in cellular function. On the membrane, they act as structural elements, serve as a pool of secondary messengers and act as a platform for membrane proteins.  Phosphatidyinositol (PI) plays an important role in signal transduction and membrane trafficking. The PI on the plasma membrane is phosphorylated to P1 and … Continue reading Workflow and Implications of membrane lipids

Discovery of novel molecular pathways linked to Insulin Resistance

Introduction Insulin resistance (IR) is a clinical and major pathological condition that occurs due to inappropriate cell response to insulin hormone and abnormal secretion in the body. The decrease in insulin sensitivity leads to the progression of many metabolic disorders such as auto-immune diseases, type-1 diabetes mellitus (T1DM), obesity, atherosclerosis, cardiovascular diseases, etc. In some … Continue reading Discovery of novel molecular pathways linked to Insulin Resistance